IHC, or Immunohistochemistry, is a technique developed and optimized by R&D Systems. It involves the fixation, microtome sectioning, and staining of paraffin-embedded tissue samples. The precise experimental conditions for each antigen of interest are determined by the investigator. This technique has been widely used in pathological diagnosis to identify cell types, recognize cell products, and understand the degree of differentiation, among other applications.
7 answers
CryptoWizardry
Fri Nov 01 2024
The initial immunohistochemical technique emerged in the 1940s.
Michele
Fri Nov 01 2024
During this time, immunofluorescence was utilized on frozen tissue samples.
DavidLee
Fri Nov 01 2024
Immunohistochemistry serves as a method for identifying specific antigens within tissues or cells.
CryptoWizardry
Fri Nov 01 2024
This early method allowed for the visualization of antigens through fluorescent labeling.
Alessandra
Fri Nov 01 2024
Advancements in immunohistochemistry continued throughout the decades.