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What is the gold standard for MDS?
What is the gold standard for MDS?
SsamziegangSerenadeMelodyHarmonySoul
Mon Nov 18 2024
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7 answers
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The gold standard for diagnosing MDS is typically based on a combination of factors including bone marrow morphology, progenitor cell count, and cytogenetics. However, the integration of Flow cytometry, particularly the use of integrated flow cytometric score (iFS), has emerged as a valuable tool to enhance diagnostic accuracy and prognostic assessment in MDS.
7 answers
Caterina
Wed Nov 20 2024
This technique involves obtaining a sample of bone marrow aspirate and preparing it as a smear.
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BonsaiStrength
Wed Nov 20 2024
Pathologists then examine the smear under a microscope to assess the morphology of the cells.
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Martino
Wed Nov 20 2024
Evaluating bone marrow morphology plays a crucial role in diagnosing myelodysplastic syndromes (MDS).
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Sofia
Wed Nov 20 2024
The aspirate smear provides detailed information about the cellular architecture and distribution within the bone marrow.
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Alessandro
Wed Nov 20 2024
It allows for the identification of abnormalities such as dysplastic changes, ring sideroblasts, and increased blasts.
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