What happened to Isabel in Saga?

So, can you tell me a bit about what happened to Isabel in Saga? I've heard some intriguing things about her journey, but I'm not entirely sure of the specifics. Did she face any major challenges or obstacles along the way? How did she overcome them? And what impact did her experiences have on her character and growth as a person? I'm really curious to hear more about her story and how it unfolds in the series.