Cryptocurrency Q&A What is the protein inhibitor of activated STAT1?

What is the protein inhibitor of activated STAT1?

Eleonora Eleonora Thu Oct 31 2024 | 7 answers 1561
I am conducting research on the protein inhibitor related to activated STAT1. I need to know the specific protein inhibitor that can effectively target and inhibit the activated form of STAT1. What is the protein inhibitor of activated STAT1?

7 answers

CryptoMaven CryptoMaven Sat Nov 02 2024
Protein inhibitors of activated STATs, known as PIAS, play a crucial role in regulating the signaling pathways of STAT proteins.

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CherryBlossomFalling CherryBlossomFalling Sat Nov 02 2024
By binding to phosphorylated STAT dimers, PIAS proteins effectively block the recognition of DNA by these dimers.

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SunlitMystery SunlitMystery Sat Nov 02 2024
This binding action subsequently inhibits the STAT-mediated signaling cascades, which are essential for cellular responses to various stimuli.

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Valentino Valentino Sat Nov 02 2024
Shuai's research in 2000 highlighted the significance of PIAS in modulating STAT activity.

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CryptoLordess CryptoLordess Fri Nov 01 2024
Among the various PIAS proteins, PIAS1 has been identified as a specific binding partner of activated STAT1.

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