I'm interested in understanding the role of phospho STAT1. Could you please explain its function and how it operates within the cellular context?
5 answers
Valentina
Thu Nov 07 2024
The process of activating Stat1 involves phosphorylation, specifically on the tyrosine residue at position 701.
CryptoDynastyLord
Thu Nov 07 2024
The transcription factor Stat1 holds a pivotal position in the body's response to interferons (IFNs).
KDramaLegendaryStarlight
Wed Nov 06 2024
Following phosphorylation on Y701, Stat1 undergoes nuclear accumulation, which is a crucial step in its function.
Skywalker
Wed Nov 06 2024
For Stat1 to exhibit full transcriptional activity and fulfill its biological role, it must undergo additional phosphorylation.
Giulia
Wed Nov 06 2024
This additional phosphorylation occurs on the serine residue at position 721.