What is the function of STAT1 and STAT3?
I'm interested in understanding the role of STAT1 and STAT3. Could you please explain their functions to me?
Where does STAT3 bind?
I'm interested in understanding the binding location of STAT3. Could you please provide information on where STAT3 binds within the cell or to which molecules it specifically interacts with?
What is STAT3 gain-of-function disease?
STAT3 gain-of-function disease is a rare genetic disorder of the immune system caused by mutations in the STAT3 gene. These mutations lead to overactivity of the gene's protein, resulting in autoimmunity and lymphoproliferative symptoms. The disease is inherited in an autosomal dominant manner and can affect multiple organs and tissues, with variable clinical manifestations including lymphadenopathy, autoimmune cytopenias, and infections.
What does STAT3 stand for?
The user wants to know the meaning of the acronym STAT3 and is seeking a definition or explanation of what it stands for.
What cytokines activate STAT3?
I'm interested in understanding which cytokines are capable of activating STAT3. Could you provide me with a list or detailed information on this topic?